Single Grain
Digital marketing agency focused on revenue-driving growth strategies
About Single Grain
Single Grain is a digital marketing agency led by CEO Eric Siu that serves companies across multiple industries including technology, e-commerce, and select healthcare clients. The agency positions itself as a partner that companies don't outgrow, claiming an average 3.2x ROI across 500+ clients.
The agency's services span paid advertising, SEO, conversion rate optimization, performance creative, data analytics, and content marketing. Single Grain emphasizes proprietary approaches including Programmatic SEO and AI-powered CRO techniques. Their methodology includes a multi-phase process from initial consultation through continuous optimization, with engagements typically starting within 1-2 weeks and full rollout within 2-4 weeks.
Case studies demonstrate results across various sectors, including some healthcare-adjacent work with SmartRent (smart home technology for properties) and Bierman Autism (healthcare services). The agency has worked with notable brands including Amazon Alexa, Nextiva, Salesforce, and Uber, though healthcare does not appear to be a primary vertical focus.
Best For
Single Grain is best suited for mid-market to enterprise technology companies and digital health startups seeking comprehensive digital marketing services with an emphasis on measurable ROI. Companies with monthly marketing budgets of $50,000+ looking for integrated campaigns across paid media, organic search, and conversion optimization will find their multi-channel approach relevant.
Key Strengths
- Demonstrated case studies showing specific metric improvements including AI search visibility gains for healthcare clients like Bierman Autism (+75% AI Overview capture, +100% Gemini visibility)
- Integrated multi-channel approach combining SEO, paid advertising, creative, and CRO rather than siloed services
- Quick engagement timeline with strategy development in 1-2 weeks and full rollout within 3 months
- Focus on revenue-driving KPIs rather than vanity metrics, with claimed 3.2x average ROI
- Experience with emerging search technologies including AI citations and LLM visibility optimization
- Access to CEO Eric Siu's marketing thought leadership through webinars and educational content
Why Choose Single Grain
Consider Single Grain when you need a performance-focused digital marketing partner with proven experience in complex B2B and technology marketing, and you're specifically looking for integrated campaigns across multiple channels. Their strength lies in combining paid media, organic search, and conversion optimization into cohesive strategies.
Expect a data-driven approach with emphasis on revenue metrics and regular optimization. Their process includes upfront strategy development and continuous monitoring, making them suitable for companies that value measurable outcomes over brand-focused marketing activities.
Healthcare Focus
Single Grain has completed select projects in healthcare-adjacent sectors, including work with SmartRent (achieving 10 monthly SQLs from LLMs valued at $126,000) and Bierman Autism (achieving +75% AI Overview capture increase and +100% new Gemini visibility). However, healthcare does not appear to be a core vertical specialization.
The agency's healthcare work focuses primarily on digital health and technology-enabled healthcare companies rather than traditional healthcare providers, payers, or health systems. No specific healthcare compliance capabilities, patient acquisition expertise, or clinical workflow understanding is evident in their public materials.
Ideal Client Profile
The ideal client is a growth-stage technology company, B2B SaaS provider, or digital health startup with marketing budgets exceeding $50,000 monthly. Organizations that need integrated digital marketing services across multiple channels and value measurable ROI over brand awareness will align well with Single Grain's performance-focused methodology and multi-channel expertise.
Specializations
Client Types
Why Choose Single Grain?
- 51-200 team members
- 1 certification verified
- Emerging Partner on Curatrix
- Verified on Curatrix
Quick Facts
- Category
- Healthcare SEO Agencies
- Company Size
- 51-200 employees
Certifications
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Profile last updated: Jan 26, 2026
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