Healthcare Companies in Fortune 500 U.S.

2025 data for 45 U.S. healthcare companies ranked in the Fortune 500

Companies

45

Total Revenue

$3.23T

Market Value

$4.87T

Total Employees

3,036,007

Showing all 45 healthcare companies
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# Company
1 3 UnitedHealth Group $400.3B
2 5 CVS Health $372.8B
3 9 McKesson $309.0B
4 10 Cencora $294.0B
5 13 Cigna $247.1B
6 15 Cardinal Health $226.8B
7 20 Elevance Health $177.0B
8 23 Centene $163.1B
9 39 Humana $117.8B
10 48 Johnson & Johnson $88.8B
11 61 HCA Healthcare $70.6B
12 65 Merck (U.S.) $64.2B
13 67 Pfizer $63.6B
14 77 AbbVie $56.3B
15 94 Bristol-Myers Squibb $48.3B
16 100 Eli Lilly $45.0B
17 107 Abbott Laboratories $42.0B
18 111 Molina Healthcare $40.6B
19 134 Amgen $33.4B
20 149 Gilead Sciences $28.8B
21 180 Danaher $23.9B
22 195 Stryker $22.6B
23 206 Tenet Healthcare $20.7B
24 211 Becton Dickinson $20.2B
25 219 GE HealthCare Technologies $19.7B
26 248 Boston Scientific $16.7B
27 271 Universal Health Services $15.8B
28 282 IQVIA Holdings $15.4B
29 288 Baxter International $15.1B
30 298 Viatris $14.7B
31 306 Regeneron Pharmaceuticals $14.2B
32 328 Labcorp Holdings $13.0B
33 331 DaVita $12.8B
34 333 Henry Schein $12.7B
35 335 Community Health Systems $12.6B
36 377 BrightSpring Health Services $11.3B
37 385 Vertex Pharmaceuticals $11.0B
38 395 Owens & Minor $10.7B
39 419 Quest Diagnostics $9.87B
40 424 Biogen $9.68B
41 435 Zoetis $9.26B
42 437 Oscar Health $9.18B
43 459 Intuitive Surgical $8.35B
44 462 Solventum $8.25B
45 483 Zimmer Biomet Holdings $7.68B

Understanding the data

Value abbreviations

  • B = Billions (e.g., $400.3B = $400.3 billion)
  • M = Millions (e.g., $850M = $850 million)
  • K = Thousands (e.g., 400K = 400,000 employees)

Data source

  • • Fortune 500 U.S. 2025 rankings
  • • Market value as of ranking date
  • • U.S. pharma, insurers, devices, providers

Key Data Insights

Analysis and highlights from the Fortune 500 U.S. healthcare companies dataset

Top 5 by Revenue

  1. 1 UnitedHealth Group
    $400B
  2. 2 CVS Health
    $373B
  3. 3 McKesson
    $309B
  4. 4 Cencora
    $294B
  5. 5 Cigna
    $247B

Top 5 by Market Cap

  1. 1 Eli Lilly
    $783B
  2. 2 UnitedHealth Group
    $479B
  3. 3 Johnson & Johnson
    $400B
  4. 4 AbbVie
    $371B
  5. 5 Abbott Laboratories
    $230B

Most Profitable

  1. 1 Merck (U.S.)
    $17B
  2. 2 UnitedHealth Group
    $14B
  3. 3 Johnson & Johnson
    $14B
  4. 4 Abbott Laboratories
    $13B
  5. 5 Eli Lilly
    $11B

Fastest Growing

  1. 1 Oscar Health
    +56.5%
  2. 2 Eli Lilly
    +32%
  3. 3 BrightSpring Health Services
    +27.6%
  4. 4 Cigna
    +26.6%
  5. 5 Molina Healthcare
    +19.3%

Largest Employers

  1. 1 UnitedHealth Group
    400,000
  2. 2 HCA Healthcare
    271,000
  3. 3 CVS Health
    259,500
  4. 4 Johnson & Johnson
    138,100
  5. 5 Abbott Laboratories
    114,000

Highest Valuation

  1. 1 Intuitive Surgical
    21.2x
  2. 2 Eli Lilly
    17.4x
  3. 3 Vertex Pharmaceuticals
    11.3x
  4. 4 Boston Scientific
    8.9x
  5. 5 Zoetis
    8.0x

Market cap / Revenue ratio

Avg. Revenue

$72B

Avg. Market Cap

$108B

Avg. Employees

67,467

Companies with Losses

7

Key Takeaways

  • UnitedHealth Group leads in revenue at $400B, more than the next two companies combined.
  • Eli Lilly has the highest market cap ($783B) and the fastest revenue growth (32%) among large pharma.
  • Intuitive Surgical commands the highest valuation multiple (21x revenue) reflecting investor confidence in surgical robotics.
  • 7 companies reported losses, including Bristol-Myers Squibb (-$8.9B) and Vertex Pharmaceuticals.
  • Health insurers dominate the top revenue spots, while pharma leads in market valuations and profitability.

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