OpenEvidence

OpenEvidence operates an AI-powered medical information platform designed for healthcare professionals at the point of care. The platform provides clinical decision support by integrating content from major medical publishers including The New England Journal of Medicine, JAMA Network, and NCCN Guidelines. The company states it has supported over 100 million AI-powered clinical consultations from U.S. doctors and other frontline clinicians.

The platform functions as an AI copilot that helps physicians make clinical decisions by retrieving and synthesizing medical evidence. OpenEvidence partners with multiple medical societies including NCCN, ACC, ADA, AAFP, AAOS, AAO-HNS, and ACEP, and maintains HIPAA compliance and SOC 2 Type II certification. The company emerged from the Mayo Clinic Platform Accelerate program and maintains medical advisors from institutions including Massachusetts General Hospital, Cleveland Clinic, UCSF, and Johns Hopkins.

The company has attracted significant venture backing from investors including Sequoia, Google Ventures, Kleiner Perkins, Nvidia, and others. OpenEvidence offers free, unlimited access to verified U.S. healthcare professionals through web and mobile applications.

Organizations should consider OpenEvidence when they need a turnkey clinical decision support platform with established medical society partnerships and extensive physician adoption. The platform suits health systems seeking to deploy an AI-powered medical information tool without building custom infrastructure.

Expect a standardized platform experience with access to premium medical content sources. The free model for verified clinicians enables rapid pilot programs and departmental adoption, though enterprise licensing terms and custom integration options are not publicly detailed.

OpenEvidence operates exclusively in healthcare, specifically targeting U.S. physicians and frontline clinicians. The platform addresses clinical decision-making at the point of care with HIPAA compliance and healthcare-specific security certifications. Partnerships with medical societies including NCCN for oncology, ACC for cardiology, ADA for diabetes, AAFP for family medicine, and others demonstrate focus on specialty-specific clinical content.

The company's medical advisor network spans multiple clinical specialties including cardiology, neurosurgery, rheumatology, gastroenterology, oncology, and others, indicating broad applicability across healthcare domains. Integration with NCCN Clinical Pathways and Guidelines specifically addresses oncology clinical workflows.

U.S.-based health systems, academic medical centers, and large physician practices seeking to deploy AI-powered clinical decision support tools to their medical staff. Organizations that value partnerships with established medical publishers and professional societies. Healthcare institutions looking for platforms with demonstrated physician adoption and usage rather than experimental or custom-built solutions.