Regenstrief Institute, Inc.

Regenstrief Institute is a healthcare research organization established in 1969 on the Indiana University-Purdue University Indianapolis campus. Founded by Sam and Myrtie Regenstrief to apply industrial engineering principles to healthcare, the institute conducts transformative research in health systems and communities while operating Regenstrief Data Services (RDS), which provides access to clinical data from the Indiana Network for Patient Care and electronic medical record warehouses.

The institute's capabilities span multiple domains including Alzheimer's and dementia research, artificial intelligence and machine learning applications, care delivery models, health disparities research, applied aging research, and health informatics. RDS offers services ranging from feasibility assessments and cohort identification to natural language processing, machine learning model operationalization, and EHR integration. The team provides data extraction, deidentification, geocoding, phenotyping, and data linkage services for researchers and healthcare organizations.

Regenstrief maintains established partnerships with IU Health and Eskenazi Health, providing direct access to their EMR systems and appointment data. The institute's nDepth™ natural language processing technology extracts clinical data from unstructured documents like physician notes, operative reports, and pathology reports, enabling more precise patient identification for research and quality improvement initiatives.

Choose Regenstrief Institute when your project requires access to comprehensive Indiana clinical data, sophisticated data science capabilities including NLP and machine learning, or when conducting federally-funded research that benefits from their established infrastructure and compliance expertise. The institute excels at complex cohort identification, registry development, and studies requiring linkage of clinical data with social determinants of health.

Expect a research-oriented partnership with methodological rigor, HIPAA-compliant data handling, and support throughout the research lifecycle from grant preparation to data delivery. The team's experience spans diverse clinical domains and they provide both technical data services and strategic guidance on protocol development.

Regenstrief Institute operates exclusively within healthcare, focusing on health systems research, clinical informatics, and population health. The organization maintains deep expertise in Alzheimer's and dementia care, aging research, health disparities, and care delivery models. Their data services specifically support HIPAA-compliant research, quality measurement, and clinical decision support.

The institute's work directly supports hospitals, health systems, and academic medical centers through services like registry development for chronic conditions, recruitment list generation for clinical trials, and extraction of quality measures. Their nDepth™ technology addresses healthcare-specific challenges in mining clinical notes and pathology reports for research and quality improvement purposes.

The ideal client is an academic researcher, health services investigator, or healthcare organization conducting population health research, clinical effectiveness studies, or quality improvement initiatives within Indiana. Organizations pursuing NIH or other federal funding that need preliminary data, letter of support, or comprehensive data extraction services aligned with academic research standards will find strong alignment with Regenstrief's capabilities and mission.