DrFirst, Inc.

DrFirst operates the largest medication management network in the United States, connecting healthcare providers, pharmacies, and patients through integrated technology solutions. Based in Rockville, Maryland, the company has served the healthcare industry for 25 years, focusing on optimizing medication workflows from prescribing through adherence. DrFirst pioneered the nation's first certified electronic prescribing of controlled substances (EPCS) solution and maintains Surescripts Gold Certification.

The company's platform encompasses three core areas: prescribing (e-prescribing with clinical decision support), adherence (patient engagement and medication access tools), and optimization (aggregating medication data from multiple sources). DrFirst serves over 40,000 providers and integrates with 260+ EHR/EMR systems and pharmacy benefit managers. Their solutions address regulatory compliance requirements including HTI-4, EPCS mandates, and PDMP integration across all 50 states.

DrFirst has received over 50 awards during its 25-year history and maintains partnerships with major healthcare technology vendors and health systems. The company serves hospitals, health systems, EHR vendors, and digital health companies with solutions designed to reduce medication errors, improve clinical workflows, and meet evolving federal and state regulatory requirements.

Choose DrFirst when medication management compliance and network connectivity are business-critical requirements. The company excels at helping EHR vendors and health systems meet regulatory deadlines without disrupting development roadmaps, providing certified, tested solutions that handle EPCS, PDMP, real-time benefit checks, and prior authorization workflows.

Organizations can expect a partnership model where DrFirst acts as an extension of internal teams, providing ongoing regulatory updates and network maintenance. The established network infrastructure eliminates the need to build individual pharmacy, PBM, and state PDMP connections, while Surescripts Gold Certification ensures compliance and reliability for prescribing workflows.

DrFirst exclusively serves the healthcare sector with 25 years of focus on medication management workflows. The company maintains deep expertise in healthcare regulatory compliance, including HIPAA, EPCS mandates across all states, PDMP integration requirements, and evolving federal rules from CMS and ASTP/ONC. Their solutions address the complete medication lifecycle from prescribing through adherence, serving hospitals, health systems, ambulatory practices, home health agencies, and behavioral health providers.

The company's healthcare specialization extends to partnerships with major EHR vendors, pharmacy benefit managers, and health IT platforms, with established protocols for protected health information exchange and medication data interoperability across fragmented healthcare systems.

The ideal client is an EHR/HIT vendor, health system, or hospital network requiring enterprise-grade medication management infrastructure and regulatory compliance expertise. Organizations facing resource constraints in keeping pace with CMS/ONC requirements, managing state-by-state PDMP variations, or building pharmacy network connections will benefit most from DrFirst's established network and turnkey solutions.