Surescripts

Surescripts operates the nation's largest health information network, connecting 2.29 million healthcare professionals and provider organizations with pharmacies, health plans, PBMs, and other stakeholders. The company processed 27.2 billion network transactions in 2024, representing virtually all insured Americans in its Master Patient Index. Surescripts focuses on transforming health data into actionable clinical and benefit intelligence throughout the patient care journey.

The platform's core capabilities span intelligent prescribing, prior authorization automation, prescription benefit and price intelligence, clinical interoperability, and value-based care analytics. Through the Surescripts Network Alliance, the company facilitates real-time health intelligence sharing at scale across EHR vendors, health systems, pharmacies, health plans, life sciences companies, and analytics vendors. The network infrastructure emphasizes reliability, security, and data quality with a focus on network integrity and compliance.

Surescripts serves the healthcare ecosystem as infrastructure rather than a direct service provider, enabling other organizations to build solutions on its network. The company's approach centers on cross-industry collaboration to address systemic healthcare challenges including medication access, prior authorization delays, and care coordination gaps.

Choose Surescripts when your organization needs to participate in national health information exchange for prescribing, prior authorization, or clinical data sharing. The company provides the infrastructure for organizations that want to avoid building point-to-point connections with thousands of individual entities.

Expect standardized integration pathways with established protocols, extensive existing network connectivity, and focus on transaction reliability and data quality. Organizations benefit from network effects—connecting once to reach virtually all insured patients, prescribers, and pharmacies. Implementation typically involves technical integration with existing systems rather than custom development.

Surescripts operates exclusively within healthcare, specifically focused on medication-related data exchange and clinical interoperability. The company serves acute care, specialty pharmacy, long-term and post-acute care settings with solutions addressing prescription safety, medication adherence, prior authorization burdens, and care transitions.

Healthcare-specific capabilities include HIPAA-compliant data exchange, integration with clinical workflows through major EHR platforms, specialty medication support for complex therapies, and value-based care analytics incorporating medication adherence and quality measures. The company maintains healthcare-specific data standards and protocols while supporting evolving requirements like electronic case reporting and alternative care delivery models.

Organizations requiring standardized connectivity to the broader healthcare ecosystem for prescription workflows, benefit verification, prior authorization, or clinical data exchange. EHR and pharmacy system vendors seeking to offer network services to their customers. Health plans and PBMs needing to share formulary and benefit information with prescribers. Life sciences companies managing patient access programs. Healthcare analytics vendors building value-based care solutions that require comprehensive medication and clinical data.